covid-19 Public date: 06.12.2021 08:58:58

22 Nov 2021

Ivermectin – COVID-19 Treatment Guidelines

Ivermectin has been shown to inhibit the replication of SARS-CoV-2 in cell cultures.13 However, pharmacokinetic and pharmacodynamic studies suggest that achieving the plasma concentrations necessary for the antiviral efficacy detected in vitro would require administration of doses up to 100-fold higher than those approved for use in humans.
Ivermectin has been shown to inhibit the replication of SARS-CoV-2 in cell cultures.13 However, pharmacokinetic and...
3 Sep 2021

Why You Should Not Use Ivermectin to Treat or Prevent COVID-19

Ivermectin tablets are approved by the FDA to treat people with intestinal strongyloidiasis and onchocerciasis, two conditions caused by parasitic worms. Using the Drug ivermectin to treat COVID-19 can be dangerous and even lethal. The FDA has not approved the drug for that purpose.
Ivermectin tablets are approved by the FDA to treat people with intestinal strongyloidiasis and onchocerciasis, two...
1 Jan 2021

Monoclonal antibodies: Overburdened hospitals are not offering this treatment against covid-19

Monoclonal antibodies — described as “unbelievable” by President Trump, who received the treatment this fall — are designed for patients newly diagnosed with covid-19, the disease caused by the coronavirus, who have a high risk of developing complications and becoming seriously ill.
Monoclonal antibodies — described as “unbelievable” by President Trump, who received the treatment this fall —...

Publisher: Science

Author:

13 Oct 2020

Found: genes that sway the course of the coronavirus

Scientist have pinned down common gene variants that are linked to the most severe cases of COVID19 and the reason why some people get very sick and others show only mild symptoms. This discovery leads to discovery of existing drugs that could be repurposed to help sick patients.
Scientist have pinned down common gene variants that are linked to the most severe cases of COVID19 and the reason why...

Publisher: STAT

Author:

12 Aug 2020

Inspired by llamas, scientists make potent anti-coronavirus agent

Inspired by a unique kind of infection-fighting antibody found in llamas, alpacas, and other camelids, a research team at the University of California, San Francisco, has synthesized a molecule that they say is among the most potent anti-coronavirus compounds tested in a lab to date
Inspired by a unique kind of infection-fighting antibody found in llamas, alpacas, and other camelids, a research team...

Publisher: STAT

Author:

22 Jul 2020

Confusion spreads over selection of priority groups for Covid-19 vaccines

On Tuesday, the National Academy of Medicine, tasked by top U.S. health officials, named an expert panel to develop a framework to determine who should be vaccinated first, when available doses are expected to be scarce. But that panel is ostensibly encroaching on the role of the Advisory Committee on Immunization Practices, a panel that has made recommendations on vaccination policy to the Centers for Disease Control and Prevention for decades, including drawing up the vaccination priority list during the 2009 H1N1 flu pandemic.
On Tuesday, the National Academy of Medicine, tasked by top U.S. health officials, named an expert panel to develop a...

Publisher: Wired

Author:

20 Jul 2020

What Does It Mean to Say a New Drug ‘Works’?

In the midst of a global crisis, scientists are trying to solve an epistemologically intractable question. Defining whether a drug “works” has never been easy, a task vexed by methodological uncertainty, commercial pressures, statistical errors, or sometimes straight-out bad practices. Facing a new disease, researchers have to rethink what success even means. Is it lower mortality? Less disability upon recovery? Faster recovery? The answers are cryptic because the questions are just educated guesses.
In the midst of a global crisis, scientists are trying to solve an epistemologically intractable question. Defining...

Publisher: NY Times

Author:

17 Jul 2020

Coronavirus Drug and Treatment Tracker

Below is an updated list of 19 of the most-talked-about treatments for the coronavirus. While some are accumulating evidence that they’re effective, most are still at early stages of research. We also included a warning about a few that are just bunk.
Below is an updated list of 19 of the most-talked-about treatments for the coronavirus. While some are accumulating...
14 Jul 2020

Decades of research on an HIV vaccine boosts the bid for one against coronavirus

Those decades of research into HIV have taught scientists an enormous amount about the immune system, honed vaccine technologies now being repurposed against the coronavirus and created a worldwide infrastructure of clinical trial networks that can be pivoted from HIV to the pathogen that causes the disease covid-19.
Those decades of research into HIV have taught scientists an enormous amount about the immune system, honed vaccine...

Publisher: POLITICO

Author:

14 Jul 2020

Moderna coronavirus vaccine shows promising results in early clinical trial

An experimental coronavirus vaccine developed by Moderna provoked an immune response without major side effects in an early-stage clinical trial, scientists reported Tuesday in the New England Journal of Medicine.The vaccine is the first developed by a U.S. company to publish clinical trial results.
An experimental coronavirus vaccine developed by Moderna provoked an immune response without major side effects in an...

Publisher: Contract Pharma

Author:

6 Jul 2020

Regeneron Starts Phase 3 Trial For Coronavirus Antibody Cocktail

Regeneron Pharmaceuticals has started late-stage clinical trials evaluating REGN-COV2, its investigational double antibody cocktail for the treatment and prevention of COVID-19. A Phase 3 trial will evaluate REGN-COV2's ability to prevent infection among uninfected people who have had close exposure to a COVID-19 patient.
Regeneron Pharmaceuticals has started late-stage clinical trials evaluating REGN-COV2, its investigational double...
1 Jul 2020

Remdesivir: How does the drug treat coronavirus and is it available in the UK?

Health officials in the US have announced that the Trump administration has bought almost the entire world’s stock of the Covid-19 drug remdesivir. Despite its ability to shorten the recovery times (by around four days) of some coronavirus patients, remdesivir has not been found to significantly improve an individual’s chances of surviving the disease.
Health officials in the US have announced that the Trump administration has bought almost the entire world’s stock of...

Publisher: euronews

Author:

23 Jun 2020

Virology and physics join forces to beat COVID-19

.In Hamburg scientists are studying the elusive protein structures that enable coronaviruses, including SARS-CoV-2, to take hold. They are trying to find out how they are able to replicate so rapidly inside human cells.
.In Hamburg scientists are studying the elusive protein structures that enable coronaviruses, including SARS-CoV-2, to...
16 Jun 2020

Coronavirus: Dexamethasone proves first life-saving drug

A cheap and widely available drug can help save the lives of patients seriously ill with coronavirus. The low-dose steroid treatment dexamethasone is a major breakthrough in the fight against the deadly virus, UK experts say. The drug is part of the world's biggest trial testing existing treatments to see if they also work for coronavirus.
A cheap and widely available drug can help save the lives of patients seriously ill with coronavirus. The low-dose...
5 May 2020

Israeli scientists discover monoclonal antibody that neutralizes SARS-CoV-2

In a significant medical breakthrough, Israel's Institute for Biological Research Institute (IIBRI) has wrapped up the development of a potential treatment for the coronavirus disease. The scientists say they have identified an antibody that neutralizes SARS-CoV-2 in vitro or outside of a living organism.
In a significant medical breakthrough, Israel's Institute for Biological Research Institute (IIBRI) has wrapped up the...
1 May 2020

What You Should Know About Remdesivir, The Potential COVID-19 Treatment

On Wednesday, researchers announced that they had “positive data” in regards to a potential treatment for COVID-19. Clinical trials for Gilead Sciences’ antiviral drug remdesivir, which was developed to treat Ebola, showed a “clear-cut positive effect in diminishing time to recover,” according to Dr. Anthony Fauci, the director of the National Institute of Allergy and Infectious Diseases.
On Wednesday, researchers announced that they had “positive data” in regards to a potential treatment for COVID-19....
27 Apr 2020

Can Estrogen and Other Sex Hormones Help Men Survive Covid-19?

As the novel coronavirus swept through communities around the world, preying disproportionately on the poor and the vulnerable, one disadvantaged group has demonstrated a remarkable resistance. Women, whether from China, Italy or the U.S., have been less likely to become acutely ill — and far more likely to survive. Which has made doctors wonder: Could hormones produced in greater quantities by women be at work?
As the novel coronavirus swept through communities around the world, preying disproportionately on the poor and the...
19 Mar 2020

Nutraceuticals have potential for boosting the type 1 interferon response to RNA viruses including influenza and coronavirus

Read about effective discoveries in the fight against the coronavirus. The talk is technical and requires knowledge of medicine and chemistry, but it also offers some remedies to lesson the effects of coronavirus like antioxidants that protect excessive lung inflammaion.
Read about effective discoveries in the fight against the coronavirus. The talk is technical and requires knowledge of...
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